One person is seriously injured following a two-vehicle accident on Highway 44. The accident happened Monday evening around 5:10 p.m. at Burr Oak Road near Oshkosh. Investigation shows a Pontiac Bonneville driven by a 35-year-old Oshkosh man was eastbound on Highway 44 when it crossed the centerline and struck a westbound Ford Excursion driven by a 61-year-old Ripon man. The Pontiac driver was transported to Theda Clark Medical Center in Neenah with life threatening injuries. The Excursion driver suffered non-life threatening injuries and was treated at Mercy Medical Center in Oshkosh. The Wisconsin State Patrol is continuing to investigate the crash.